By Richard Barakat FACS, Andrew Berchuck, Maurie Markman MD, Marcus E. Randall MD FACR
Read Online or Download Principles and Practice of Gynecologic Oncology PDF
Similar obstetrics & gynecology books
(Martin Dunitz) long island Univ. , manhattan urban. Atlas for postgraduates fascinated about the surgical administration of gynecological malignancy. incorporates a complete description of nearly all of investigative and surgeries required of the gynecological oncologist. provides transparent written and pictorial guide.
The finest textual content in gynecology is in its Fourteenth version, completely revised and up to date and now in complete colour all through. prepared into 8 sections, this complete and basic gynecological textbook presents suggestions for the administration of particular gynecological stipulations. the 1st sections conceal rules of perform and preliminary evaluate and the proper uncomplicated technological know-how.
This ebook brings jointly the main up to date information regarding the body structure of progestogens. This quantity addresses the bidirectional communique among hormones, fertility, tumors, and autoimmunity. It presents the elemental technological know-how and scientific views of progestogens that have now not been formerly to be had in a single quantity.
This publication addresses methodological facets of epidemiological reviews on maternal drug use in being pregnant. Discussing the prevailing assets of errors and the way they could produce fallacious conclusions, it examines quite a few epidemiological ideas and assesses their strengths and weaknesses. those refer either to the id of results (with specified emphasis on congenital malformations) and to the kinds of publicity (drug use).
Extra resources for Principles and Practice of Gynecologic Oncology
And international collaborative studies (248–251). The most common HPV types in descending order of frequency are HPV types 16, 18, 45, 31, 33, 52, 58 and 35, together responsible for approximately 90% of all cervical cancers worldwide. Persistent HPV16 infection is an extremely strong risk factor for subsequent diagnosis of CIN3 and invasive cancer and has been classified as a Class 1 human carcinogen by the IARC (231). HPV types are more predictive of risk than subtleties of minor and equivocal cytopathic effects, colposcopic findings, or behavioral cofactors like smoking.
Blood groups A and AB were associated with elevated risks of hydatidiform mole in one study but not in another (350,351). These findings may support a role for genetic EPI DEM IOLOGY OF GYN ECOLOGIC CANCERS 21 factors or immunologic factors related to the histocompatibility of maternal and trophoblastic tissues. Menstrual, Reproductive, and Anthropometric Risk Factors In several studies that have adjusted for the effects of late maternal age, parous women have remained at a substantially reduced risk of GTD compared with nulliparous women, with some evidence of further reductions in risk with multiple births (350,352,353).
An epidemiologic model of the natural history of cervical carcinogenesis. The major steps in cervical carcinogenesis can be broadly categorized in the following stages: (I) exposure/acquisition of new human papillomavirus (HPV) infection that may cause transient cytological changes, a majority of which clear spontaneously; (II) persistence of few carcinogenic HPV infections and progression to precancerous lesions (cervical intraepithelial neoplasia 3 [CIN3]); and (III) development of invasion. The pictures in the top row show cytological changes and those in the bottom row show corresponding colposcopic impressions of the various stages of the natural history of cervical carcinogenesis.