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Term ‘saccade’ and the first appreciation of the John M. Findlay is in the Department of jerky quality of eye scanning. Javal, a distin- Psychology, University of Durham, South Road, guished French ophthalmologist, is now often Durham DH1 3LE, UK. ©2005 Nature Publishing Group 321 T. WATSON/ALAMY Early views of viewing ESSAY NATURE|Vol 437|15 September 2005 Dirac’s hidden geometry Paul Dirac insisted that his approach to quantum physics was geometric not algebraic. But where is the evidence of this in his pioneering, algebra-rich papers?

Phys. Rev. B 70, 195301 (2004). 10. Berger, L. Phys. Rev. B 54, 9353–9358 (1996). 11. Slonczewski, J. C. J. Magn. Magn. Mater. 159, L1–L7 (1996). 12. Huygens, C. Oeuvres Complètes de Christiaan Huygens (ed. ) (Société Hollandaise des Sciences, The Hague, 1893). GENOMICS Massively parallel sequencing Yu-Hui Rogers and J. Craig Venter A sequencing system has been developed that can read 25 million bases of genetic code — the entire genome of some fungi — within four hours. The technique may provide an alternative approach to DNA sequencing.

The technique uses a sequencing-by-synthesis8 method developed by Uhlen and colleagues, in which DNA ©2005 Nature Publishing Group Figure 1 | Speeding up sequencing. 4. The traditional microlitre-scale approach requires a longer processing time per production cycle, substantially more support equipment, a larger facility and more labour than the picolitre-scale approach. complementary to each template strand is synthesized. The nucleotide bases used for sequencing release a chemical group as the base forms a bond with the growing DNA chain, and this group drives a light-emitting reaction in the presence of specific enzymes and luciferin.

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