Download Fetal-Placental Disorders by Nicholas S. Assali (Eds.) PDF

By Nicholas S. Assali (Eds.)

Show description

Read or Download Fetal-Placental Disorders PDF

Best obstetrics & gynecology books

An atlas of gynecologic oncology

(Martin Dunitz) big apple Univ. , big apple urban. Atlas for postgraduates occupied with the surgical administration of gynecological malignancy. contains a complete description of nearly all of investigative and surgeries required of the gynecological oncologist. provides transparent written and pictorial guideline.

Berek & Novak's Gynecology (Berek and Novak's Gynecology)

The premiere textual content in gynecology is in its Fourteenth variation, completely revised and up to date and now in complete colour all through. geared up into 8 sections, this finished and basic gynecological textbook presents tips for the administration of particular gynecological stipulations. the 1st sections disguise ideas of perform and preliminary evaluation and the correct uncomplicated technology.

Progestogens in Obstetrics and Gynecology

This publication brings jointly the main updated information regarding the body structure of progestogens. This quantity addresses the bidirectional communique among hormones, fertility, tumors, and autoimmunity. It presents the fundamental technology and scientific views of progestogens that have no longer been formerly to be had in a single quantity.

Drugs During Pregnancy: Methodological Aspects

This booklet addresses methodological points of epidemiological reviews on maternal drug use in being pregnant. Discussing the prevailing assets of blunders and the way they could produce improper conclusions, it examines a variety of epidemiological options and assesses their strengths and weaknesses. those refer either to the id of results (with unique emphasis on congenital malformations) and to the kinds of publicity (drug use).

Additional info for Fetal-Placental Disorders

Sample text

C. Metabolic Disorders. Various metabolic disorders may affect pla­ cental transfer. Toxemia, other hypertensive disorders of pregnancy, and diabetes are associated with a variety of vascular changes. Several workers have reported that the rate of placental sodium trans- 1. DISORDERS OF PLACENTAL TRANSFER 47 fer is decreased in toxemia {76, 77, 106, 175). Uric acid, the metabolic end product of the purine component of nucleic acids, is often elevated in patients with toxemia. However, Hayashi and his co-workers {H8) found no difference in the catabolism of nucleotide derivatives by these placentas, as compared with controls.

Thus while it is only reasonable that placental growth should proceed independently its growth will probably be somewhat re­ lated to ultimate fetal size. While several workers report that the rate of placental growth decreases during the last month of gestation {156, 159), other workers report that the growth is linear, at least until the fetus weighs about 3500 gm {4, 86). Aherne {4) reported that during the last half of pregnancy the placenta grows continuously at about a two-thirds power of the fetal weight.

Whether irradiation damages DNA, and thereby the enzyme systems involved with active transport, remains to be established. In summary, as normal gestation proceeds, there is thinning of the cytotrophoblast cello and both clumping and thinning of syncytiotropho­ blast. Various degenerative changes in the trophoblast cells, along with increasing fibrin deposition and calcification undoubtedly affect the vari­ ous placental transfer mechanisms. For those substances whose exchange is limited by blood flow rather than diffusion these changes in spatial relations probably have little effect.

Download PDF sample

Rated 5.00 of 5 – based on 37 votes